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Student and Postdoctoral Fellow Events

Student Travel Awards Deadline October 9, 2007

Student Event Planner

Student/Postdoctoral Fellow Mixer
Sunday, March 16, 7:30 PM–8:30 PM

Regional Chapter Student Representatives Meeting
Monday, March 17, 7:00 AM to 8:30 AM Business meeting

Representatives will conduct their business meeting.

In Vitro Toxicology Lecture for Students:
Monday, March 17, 12:15 PM–1:30 PM
Lecturer: Yvonee Will, Pfizer, Inc., San Diego, CA
Title: Development of In Vitro Screening Tools to Test for Drug-Induced Mitochodrial Toxicities

It is estimated that only 50% of the animal studies predict human efficacy and more importantly human toxicity. In addition, the use of animals should be minimized as much as possible for ethical reasons. Today, there are vigorous, ongoing national and international research and policy efforts to develop alternatives to animal testing. The efforts focus on both in vitro and in silico approaches and methods. For example, the National Toxicology Program (NTP) at the National Institute of Environmental Health Sciences (NIEHS) created the NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) in 1998.

Mitochondrial dysfunction is a common mechanism of drug-induced toxicity for a variety of therapeutics, such as certain antiviral drugs, lipid-lowering drugs, NSAIDs and certain cancer chemotherapeutics. Therefore, the early identification of drug candidates that potentially disrupt mitochondrial function is of significant importance in drug discovery. In the past few years we have developed organelle and cell based in vitro screens to detect potential mitochondrial toxicities. These include oxygen sensors to measure mitochondrial respiration in isolated mitochondria and cells, immunocapture of individual electron transport chain proteins that can identify inhibitors of mitochondrial electron transport, and metabolic profiling using oxygen and pH measurements. We discuss the strength and limitations of new applicable high throughput screens and provide recommendations of where to position these assays within the drug development process.

Specialty Section Student Representatives Meeting
Tuesday, March 18, 7:00 AM to 8:30 AM Business meeting

Representatives will conduct their business meeting.

Postdoctoral Assembly Luncheon
Tuesday, March 18, 12:00 NOON-1:15 PM

Amidst scrambling to attend all of the symposia, poster sessions, and social events at the meeting, this will be time for postdocs to kick back and relax! All postdoctoral fellows are invited to a casual, fun-filled luncheon organized by the Postdoctoral Assembly (PDA). We will announce the first recipients of the Best Postdoctoral Publication Awards and acknowledge the postdocs who received awards this year from Specialty Sections and Regional Chapters. The newly elected PDA Board members for 2008-09 will also be introduced and will present a short overview of accomplishments and future directions for the PDA. This is a great opportunity for you to meet and congratulate your postdoctoral colleagues and check out opportunities to volunteer and assume leadership roles within SOT. There will be a drawing for prizes. Postdocs can reserve a ticket when registering for the Annual Meeting.

Student Advisory Committee Meeting
Wednesday, March 19, 7:00 AM-8:30 AM Business meeting

Current and incoming Student Advisory Council members will conduct their business meeting, then meet with SOT Council.

Lunch with an Expert
Date and time varies by group (Meet at Bulletin Board in Registration Area)

This event is an informal gathering of a small group of students and a Toxicology Expert. Sign up via the Student Services section of the SOT Web site. The groups are matched by research interests and the Expert for each group identifies a time and place to assemble. Details for the group meeting will be sent advance of meeting.